戴祯

  • 博士
  • 办公室:F202
  • 研究员,干细胞转基因克隆研究组
  • 电话:020-32015304
  • 研究骨干,中科院再生生物学重点实验室
  • 电子邮箱:dai_zhen@gibh.ac.cn
个人简介
2011,2014年在吉林大学分别获得生物技术专业学士学位,生物化学与分子生物学专业硕士学位,2014年-2018年在德国汉诺威医学院获得分子医学博士学位,并于2018-2020年在德国汉诺威医学院从事博士后研究。2021年3月任中国科学院广州生物医药与健康研究员。
研究兴趣
长期从事肝脏再生,肝病的细胞治疗,肝脏3D类器官,转分化诱导性肝样细胞等研究。
发表论文
(代表性5篇)
1. Zhen Dai, Guangqi Song, Asha Balakrishnan, Taihua Yang, Qinggong Yuan, Selina Möbus, Anna-Carina Weiss, Martin Bentler, Jimin Zhu, Xuemei Jiang, Xizhong Shen, Heike Bantel, Elmar Jaeckel, Andreas Kispert, Arndt Vogel, Anna Saborowski, Hildegard Büning, Michael P. Manns, Tobias Cantz, Michael Ott#, Amar Deep Sharma#. Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells. Gut, (Editor's Choice) 2020
2. Zhen Dai, Michael Ott, Amar Deep Sharma. Equal opportunity offer for all hepatocytes. Journal of hepatology, 2020
3. Simon Krooss*, Zhen Dai* (co-first author), Florian Schmidt, Alice Rovai, Julia Fakhiri, Akshay Dhingra, Qinggong Yuan, Taihua Yang, Asha Balakrishnan, Lars Steinbrück, Sangar Srivaratharajan, Michael Peter Manns, Axel Schambach, Dirk Grimm, Jens Bohne, Amar Deep Sharma#, Hildegard Büning#, Michael Ott#. Ex/in vivo gene editing in hepatocytes using “all-in-one” CRISPR-AAV vectors with a self-linearizing repair template. iScience, 2020 (F1000推荐)
4. Dakai Yang*, Zhen Dai* (co-first author), Taihua Yang, Asha Balakrishnan, Qinggong Yuan, Florian W.R. Vondran, Heiner Wedemeyer, Michael Ott, Tobias Cantz, Amar Deep Sharma. MicroRNA-125b-5p regulates hepatocyte proliferation during the termination phase of liver regeneration. Hepatology communications, 2020
5. Yicheng Zhao*, Zhen Dai* (co-first author), Yang Liang, Ming Yin, Kuiying Ma, Mei He, Hongsheng Ouyang#, Chun-Bo Teng#. Sequence-specific inhibition of microRNA via CRISPR/CRISPRi system. Scientific.Reports, 2014
 
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