秦大江

  • 博士,硕士生导师
  • 办公室:A425
  • 研究员,诱导多能干细胞技术研究组
  • 电话:020-32015301
  • 研究骨干,中科院再生生物学重点实验室
  • 电子邮箱:qin_dajiang@gibh.ac.cn
个人简介
“广东特支计划”百千万工程青年拔尖人才,中国科学院广州生物医药与健康研究院重大项目与国际合作办公室主任;广州再生医学与健康广东省实验室基础研究与国际合作部副部长。
博士毕业于香港大学李嘉诚医学院生物医学系,2007年在我国率先突破体细胞重编程为多能干细胞的iPS技术。
研究兴趣
主要从事疾病iPS模型与iPS技术改进应用研究,并主持国家干细胞库南方库工作。
发表论文
(代表性5篇)
1. Chong CM, Ke M, Tan Y, Huang Z, Zhang K, Ai N, Ge W, Qin D*, Lu JH*, Su H*. Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling. Cell Death Dis. 2018, 9(9): 879. 
2. Yuan Tan, Minjing Ke, Zhijian Huang, Cheong-Meng Chong, Xiaotong Cen, Jia-HongLu, Xiaoli Yao*, Dajiang Qin*, Huanxing Su*. Hydroxyurea facilitates manifestation of disease relevant phenotypes in patients-derived iPSCs-based modeling of late-onset Parkinson’s disease. Aging and Disease. 2019, 10(5): 1037-1048.
3. Su H, Wang L, Cai J, Yuan Q, Yang X, Yao X, Wong WM, Huang W, Li Z, Wan JB, Wang Y, Pei D, So KF, Qin D*, Wu W*. Transplanted motoneurons derived from human induced pluripotent stem cells form functional connections with target muscle. Stem Cell Res. 2013, 11(1): 529-539.
4. Qin DJ, Gan Y, Shao K, Wang H, Li W, Wang T, He W, Xu J, Zhang Y, Kou Z, Zeng L, Sheng G, Esteban MA, Gao S, Pei DQ*. Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors. Journal of Biological Chemistry. 2008, 283(48): 33730-33735. 
5. Qin DJ, Li W, Zhang J, Pei DQ*. Direct generation of ES-like cells from unmodified mouse embryonic fibroblasts by Oct4/Sox2/Myc/Klf4. Cell Research. 2007, 17(11): 959-962.
个人履历