单永礼

  • 博士
  • 办公室:E404
  • 副研究员,干细胞多能性维持研究组
  • 电话:020-32015236
  • 研究骨干,中科院再生生物学重点实验室
  • 电子邮箱:shan_yongli@gibh.ac.cn
个人简介

22021.01至今 中国科学院广州生物医药与健康研究院 副研究员
2018.09-2021.01 南方医科大学南方医院 博士后
2018.01-2018.08 中国科学院广州生物医药与健康研究院 助理研究员
2012.09-2018.01 中国科学院广州生物医药与健康研究院 博士
2008.09-2012.06 安徽大学 学士

研究兴趣

人多能干细胞命运决定的表观遗传调控机制研究;人滋养层干细胞的获取及胎盘发育相关疾病机制研究。

发表论文

(代表性5篇)
1. Yongli Shan#; Yanqi Zhang#; Yuan Zhao#; Tianyu Wang; Jingyuan Zhang; Jiao Yao; Ning Ma; Zechuan Liang; Wenhao Huang; Ke Huang; Tian Zhang; Zhenghui Su; Qianyu Chen; Yanling Zhu; Chuman Wu; Tiancheng Zhou; Wei Sun; Yanxing Wei; Cong Zhang; Chenxu Li; Shuquan Su; Baojian Liao; Mei Zhong; Xiaofen Zhong; Jinfu Nie; Duanqing Pei; Guangjin Pan*. JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells, Nature Communications, 2020, 11 (1): 382.
2. Yongli Shan#; Zechuan Liang#; Qi Xing; Tian Zhang; Bo Wang; Shulan Tian; Wenhao Huang; Yanqi Zhang; Jiao Yao; Yanling Zhu; Ke Huang; Yujian Liu; Xiaoshan Wang; Qianyu Chen; Jian Zhang; Bizhi Shang; Shengbiao Li; Xi Shi; Baojian Liao; Cong Zhang; Keyu Lai; Xiaofen Zhong; Xiaodong Shu; Jinyong Wang; Hongjie Yao; Jiekai Chen; Duanqing Pei; Guangjin Pan*. PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naive ESCs, Nature Communications, 2017, 8 (1): 672.
3. Lu Xiao#, Lishi Ma#, Zhijian Wang, Yanhong Yu, Stephen J. Lye, Yongli Shan* and Yanxing Wei*. Deciphering a distinct regulatory network of TEAD4, CDX2 and GATA3 in humans for trophoblast transition from embryonic stem cells. Biochim Biophys Acta - Molecular Cell Research, 2020, 1867: 118736.
4. Ning Ma#; Yongli Shan#; Baojian Liao#; Guanyi Kong#; Cheng Wang; Ke Huang; Hui Zhang; Xiujuan Cai; Shubin Chen; Duanqing Pei; Nansheng Chen* and Guangjin Pan*. Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in beta-Thalassemia Induced Pluripotent Stem Cells (iPSCs), Journal of Biological Chemistry, 2015, 290 (19): 12079-12089. 
5. Yongli Shan*; Lishi Ma; Cong Zhang; Yanqi Zhang; Jingyuan Zhang; Lu Xiao; Yanxing Wei; Yu Yanhong*. Generation of two RNF2 homozygous knockout human embryonic stem cell lines by CRISPR/Cas9 system, Stem Cell Research, 2020, 47: 101885.
 

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